Quality Control of Cardiac Sarcomere Protein and BAG3: Repairing the Engine without Stopping the Car
Clinical physicians, physician-scientists, basic scientists, other healthcare professionals, and trainees require regular updates on mechanisms, novel therapeutics, and medical and surgical technologies to manage cardiovascular diseases and on cardiovascular basic, translational, and clinical science. The series aims to expand the knowledge of learners specifically with regard to the pathophysiology and physiology of cardiovascular disease, the mechanisms of cardiovascular science and clinical studies, the analysis and interpretation of results, and the integration of findings into science and clinical practice. A focus of the series will be to discuss the basic science underlying cardiovascular clinical studies and professional guidelines and thereby promote a wider dissemination of this information to achieve evidence-based patient care.
Physicians, fellows, residents., and other healthcare providers.
At the conclusion of the session, the participants should be able to:
Explain the role of myocardial contractility in heart failure and the importance of the sarcomere.
Recognize the importance of protein quality control mechanisms in the heart and the emerging role of BAG3 in these pathways.
Describe the evidence that BAG3 is critical for quality control and function of sarcomere protein in human and animal models of heart failure.
Baylor College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Baylor College of Medicine designates this enduring material activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
- 1.00 AMA PRA Category 1 Credit™
- 1.00 Participation