In this Discovery Clinical Pathological Conference (CPC), Dr. Paige Farinholt, Resident, Department of Medicine at Baylor College of Medicine, introduces the patient case. The patient is a 39-year old woman with a history of an unspecified learning disability and chronic migraines who presents with 3 days of altered mental status and vision changes.

Dr. Elisha Acosta, Assistant Professor in the Department of Medicine at Baylor College of Medicine, serves as the faculty discussant for this case. She discusses pertinent information from the history, physical examination, and laboratory investigations. Dr. Acosta gives an overview of her differential diagnosis and discusses the next steps she would take in the care of this patient.

Subsequently, Dr. Farinholt returns to give further lab results for the patient, Dr. V. Reid Sutton, Professor of Molecular and Human Genomics at Baylor College of Medicine, offers his expert opinion on the patient's case, focusing on disease pathophysiology, diagnostic strategies, and treatment options. Dr. Farinholt concludes the CPC by reviewing the clinical course of the presented patient.